Sanger, Gareth J: search on Z-Library

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1

Ghrelin and motilin receptors as drug targets for gastrointestinal disorders

Sanger, Gareth J., Furness, John B.

Journal:

Nature Reviews Gastroenterology and Hepatology (formerly Nature Clinical Practice Gastroenterology and Hepatology)

Year:

2015

Language:

english

File:

PDF, 458 KB

english, 2015

2

Dorsal root ganglion neurons show increased expression of the calcium channel α2δ-1 subunit following partial sciatic nerve injury

Richard A Newton, Sharon Bingham, Patrick C Case, Gareth J Sanger, Sally N Lawson

Journal:

Molecular Brain Research

Year:

2001

Language:

english

File:

PDF, 864 KB

english, 2001

3

Treatment of nausea and vomiting: Gaps in our knowledge

Gareth J. Sanger, Paul L.R. Andrews

Journal:

Autonomic Neuroscience

Year:

2006

Language:

english

File:

PDF, 245 KB

english, 2006

4

The Benefits of Olanzapine in Palliating Symptoms

Davis, Mellar P., Sanger, Gareth J.

Journal:

Current Treatment Options in Oncology

Year:

2021

File:

PDF, 440 KB

2021

5

Novel approaches and clinical opportunity for gastrointestinal prokinetic drugs

Richard A. Borman, Gareth J. Sanger

Journal:

Drug Discovery Today: Therapeutic Strategies

Year:

2007

Language:

english

File:

PDF, 118 KB

english, 2007

6

5-Hydroxytryptamine and the gastrointestinal tract: where next?

Gareth J. Sanger

Journal:

Trends in Pharmacological Sciences

Year:

2008

Language:

english

File:

PDF, 414 KB

english, 2008

7

5-HT4 receptor antagonism does not affect motor and reward mechanisms in the rat

Charlie Reavill, Jon P. Hatcher, V.Ann Lewis, Gareth J. Sanger, Jim Hagan

Journal:

European Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 555 KB

english, 1998

8

Selective and functional 5-hydroxytryptamine3 receptor antagonism by BRL 43694 (granisetron)

Gareth J. Sanger, David R. Nelson

Journal:

European Journal of Pharmacology

Year:

1989

Language:

english

File:

PDF, 902 KB

english, 1989

9

New target profiling for gastrointestinal disorders: where are we going?

Sanger, Gareth J

Journal:

Current Opinion in Pharmacology

Year:

2012

Language:

english

File:

PDF, 139 KB

english, 2012

10

Tu1811 Cortical & Physiological Responses to Visually Induced Motion Sickness

Farmer, Adam D., Ban, Vin Fei, Sanger, Gareth J., Coen, Steven J., Andrews, Paul, Azi, Qasim

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 292 KB

english, 2014

11

Thermal, But Not Mechanical, Nociceptive Behavior is Altered in the Zucker Diabetic Fatty Rat and Is Independent of Glycemic Status

Valerie Piercy, Stephen E Banner, Amit Bhattacharyya, Andrew A Parsons, Gareth J Sanger, Stephen A Smith, Sharon Bingham

Journal:

Journal of Diabetes and its Complications

Year:

1999

Language:

english

File:

PDF, 211 KB

english, 1999

12

Visually induced nausea causes characteristic changes in cerebral, autonomic and endocrine function in humans

Farmer, Adam D., Ban, Vin F., Coen, Steven J., Sanger, Gareth J., Barker, Gareth J., Gresty, Michael A., Giampietro, Vincent P., Williams, Steven C., Webb, Dominic L., Hellström, Per M., Andrews, Paul

Journal:

The Journal of Physiology

Year:

2015

Language:

english

File:

PDF, 564 KB

english, 2015

13

RQ-00201894: A motilin receptor agonist causing long-lasting facilitation of human gastric cholinergically-mediated contractions

Broad, John, Takahashi, Nobuyuki, Tajimi, Masaomi, Sudo, Masaki, Góralczyk, Adam, Parampalli, Umesh, Mannur, Kesava, Yamamoto, Toshinori, Sanger, Gareth J.

Journal:

Journal of Pharmacological Sciences

Year:

2016

Language:

english

File:

PDF, 831 KB

english, 2016

14

5-Hydroxytryptamine (5-HT3) receptor antagonists. 1. Indazole and indolizine-3-carboxylic acid derivatives

Bermudez, Jose, Fake, Charles S., Joiner, Graham F., Joiner, Karen A., King, Frank D., Miner, Wesley D., Sanger, Gareth J.

Journal:

Journal of Medicinal Chemistry

Year:

1990

Language:

english

File:

PDF, 807 KB

english, 1990

15

Increased defaecation caused by 5-HT4 receptor activation in the mouse

Stephen E. Banner, Martin I. Smith, Darren Bywater, Laramie M. Gaster, Gareth J. Sanger

Journal:

European Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 628 KB

english, 1996

16

Inhibition of cisplatin-induced vomiting by selective 5-hydroxytryptamine M-receptor antagonism

Wesley D. Miner, Gareth J. Sanger

Journal:

British Journal of Pharmacology

Year:

1986

Language:

english

File:

PDF, 317 KB

english, 1986

17

Excitatory and inhibitory neuroanally-mediated actiens of orexin-A and melaniaconcentrating hormone (MCH) in human isolated colon

Gareth J. Sanger, SmithKline Beecham, Romana Kuchai, Mike Morgan

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 170 KB

english, 2001

18

Tu1873 Evidence for Reduced Visceral Nociceptors Activation With Age During Appendicitis

Cibert-Goton, Vincent, Kung, Victor W., Hockley, James R., Blackshaw, Ashley, Knowles, Charles H., Sanger, Gareth J., Bulmer, David C.

Journal:

Gastroenterology

Year:

2015

Language:

english

File:

PDF, 761 KB

english, 2015

19

COVIDâ19, nausea and vomiting

Andrews, Paul L.R., Cai, Weigang, Rudd, John A., Sanger, Gareth J.

Journal:

Journal of Gastroenterology and Hepatology

Year:

2020

File:

PDF, 1.43 MB

2020

20

Prokineticin-2, motilin, ghrelin and metoclopramide: Prokinetic utility in mouse stomach and colon

Anna K. Bassil, Narinder B. Dass, Charles D. Murray, Alison Muir, Gareth J. Sanger

Journal:

European Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 362 KB

english, 2005

21

Anti-emetic activity of ghrelin in ferrets exposed to the cytotoxic anti-cancer agent cisplatin

John A. Rudd, Man P. Ngan, Man K. Wai, Andrew G. King, Jason Witherington, Paul L.R. Andrews, Gareth J. Sanger

Journal:

Neuroscience Letters

Year:

2006

Language:

english

File:

PDF, 126 KB

english, 2006

22

Inhibition by tianeptine of neuronally mediated contractions in the rat isolated gastrointestinal tract

Victoria N. Bolton, Anna K. Bassil, Kevin Lee, Gareth J. Sanger

Journal:

Pharmacological Research

Year:

2008

Language:

english

File:

PDF, 457 KB

english, 2008

23

W2074 Long-Term Consequences of Neo-Adjuvant Chemotherapy for Oesophago-Gastric Cancer On Gastric Contractility and Innervation

Sung, Edmond Z., Jarvie, Emma, James, Sean, Menon, Vinod S., Borman, Richard A., Snead, David, Sanger, Gareth J., Nwokolo, Chuka U.

Journal:

Gastroenterology

Year:

2009

Language:

english

File:

PDF, 46 KB

english, 2009

24

Functional and anatomical deficits in visceral nociception with age

Cibert-Goton, Vincent, Kung, Victor W.S., McGuire, Cian, Hockley, James R.F., Tranter, Michael M, Dogra, Harween, Belai, Abi, Blackshaw, L. Ashley, Sanger, Gareth J., Knowles, Charles H., Araujo, Edua

Journal:

Year:

2019

File:

PDF, 7.64 MB

2019

25

Aryl sulphonyl amides as potent agonists of the growth hormone secretagogue (ghrelin) receptor

Jason Witherington, Lee Abberley, Benjamin R. Bellenie, Rio Boatman, Katharine Collis, David K. Dean, Alessandra Gaiba, N. Paul King, Nicola Shuker, Jon G.A. Steadman, Andrew K. Takle, Gareth Sanger,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 149 KB

english, 2009

26

Identification of genes for the ghrelin and motilin receptors and a novel related gene in fish, and stimulation of intestinal motility in zebrafish (Danio rerio) by ghrelin and motilin

Catharina Olsson, Joanna D. Holbrook, Giulia Bompadre, Elisabeth Jönsson, Charles H.V. Hoyle, Gareth J. Sanger, Susanne Holmgren, Paul L.R. Andrews

Journal:

General and Comparative Endocrinology

Year:

2008

Language:

english

File:

PDF, 1.72 MB

english, 2008

27

Defensive and pathological functions of the gastrointestinal NK3 receptor

Gareth J. Sanger, Bishwa R. Tuladhar, Lionel Bueno, John B. Furness

Journal:

Vascular Pharmacology

Year:

2006

Language:

english

File:

PDF, 158 KB

english, 2006

28

A prostaglandin analogue which potently relaxes human uterus but not gut muscle

Gareth J. Sanger, Anne Jackson, Alan Bennett

Journal:

European Journal of Pharmacology

Year:

1982

Language:

english

File:

PDF, 209 KB

english, 1982

29

Demonstration of Functional Neuronal β3-Adrenoceptors Within the Enteric Nervous System

Selim Cellek, Ramkumar Thangiah, Anna K. Bassil, Colin A. Campbell, Karen M. Gray, Jennifer L. Stretton, Olutunde Lalude, Shanmugam Vivekanandan, Alan Wheeldon, Wendy J. Winchester, Gareth J. Sanger,

Journal:

Gastroenterology

Year:

2007

Language:

english

File:

PDF, 7.66 MB

english, 2007

30

Human native kappa opioid receptor functions not predicted by recombinant receptors: Implications for drug design

Broad, John, Maurel, Damien, Kung, Victor W. S., Hicks, Gareth A., Schemann, Michael, Barnes, Michael R., Kenakin, Terrence P., Granier, Sébastien, Sanger, Gareth J.

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.42 MB

english, 2016

31

The prokinetic-like activity of ghrelin in rat isolated stomach is mediated via cholinergic and tachykininergic motor neurones

Anna K. Bassil, Narinder B. Dass, Gareth J. Sanger

Journal:

European Journal of Pharmacology

Year:

2006

Language:

english

File:

PDF, 271 KB

english, 2006

32

Abdominal vagal afferent neurones: an important target for the treatment of gastrointestinal dysfunction

Paul L.R Andrews, Gareth J Sanger

Journal:

Current Opinion in Pharmacology

Year:

2002

Language:

english

File:

PDF, 72 KB

english, 2002

33

GABAb receptor-mediated inhibition of cholinergic function in mouse ileum requires the GABAb1 subunit

Gareth J. Sanger, Mona Munonyara, Haydn Prosser, Mene N. Pangalos, A Jackie Hunter, Mike E. Parsons

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 192 KB

english, 2001

34

N-[(1-Butyl-4-piperidinyl)methyl]-3,4- dihydro-2H-[1,3]oxazino[3,2-a]indole- 10-carboxamide hydrochloride: the first potent and selective 5-HT4 receptor antagonist amide with oral activity.

Gaster, Laramie M., Joiner, Graham F., King, Frank D., Wyman, Paul A., Sutton, Jonathan M., Bingham, Sharon, Ellis, Elizabeth S., Sanger, Gareth J., Wardle, Kay A.

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 952 KB

english, 1995

35

Making Sense of Emesis, Pruritus, 5-HT and 5-HT 3 Receptor Antagonists

Sanger, Gareth J, Twycross, Robert

Journal:

Progress in Palliative Care

Year:

1996

Language:

english

File:

PDF, 359 KB

english, 1996

36

Gastrointestinal pharmacology: challenges ahead

Sanger, Gareth J.

Journal:

Frontiers in Pharmacology

Year:

2010

Language:

english

File:

PDF, 176 KB

english, 2010

37

Reversal of Pathogen-Induced Barrier Defects in Intestinal Epithelial Cells by Contra-pathogenicity Agents

Choudhry, Naheed, Scott, Flora, Edgar, Meghan, Sanger, Gareth J., Kelly, Paul

Journal:

Digestive Diseases and Sciences

Year:

2020

File:

PDF, 1.63 MB

2020

38

Drugs targeting functional bowel disorders: insights from animal studies

Gareth J Sanger, Gareth A Hicks

Journal:

Current Opinion in Pharmacology

Year:

2002

Language:

english

File:

PDF, 64 KB

english, 2002

39

The effects of granisetron, ICS 205–930 and ondansetron on the visceral pain reflex induced by duodenal distension

Helen E. Moss, Gareth J. Sanger

Journal:

British Journal of Pharmacology

Year:

1990

Language:

english

File:

PDF, 921 KB

english, 1990

40

490 Studies of the Psychophysiological Markers and the Brain Processing of Nausea in Healthy Humans Using a Novel Virtual Reality Video

Kee S. Ng, Yang C. Chua, Vin Fei Ban, Michael Gresty, Steven J. Coen, Gareth J. Sanger, Steven C. Williams, Gareth Barker, Paul Andrews, Minh Luu, James K. Ruffle, Roy J. Heng, David Sims, Elizabeth B

Journal:

Gastroenterology

Year:

2012

Language:

english

File:

PDF, 131 KB

english, 2012

41

Effects of ageing on myenteric neuronal number and neuromuscular function in the human colon

Kung, Victor, Broad, John, Carroll, Rebecca, Knowles, Charles, Sanger, Gareth

Journal:

Year:

2016

Language:

english

File:

PDF, 61 KB

english, 2016

42

Analysis of the ghrelin receptor-independent vascular actions of ulimorelin

Broad, John, Callaghan, Brid, Sanger, Gareth J., Brock, James A., Furness, John B.

Journal:

European Journal of Pharmacology

Year:

2015

Language:

english

File:

PDF, 464 KB

english, 2015

43

Increased gastric cholinergic activity evoked by 5-hydroxy-L-tryptophan in the rat

Gareth J. Sanger, Christine M. McClelland

Journal:

European Journal of Pharmacology

Year:

1986

Language:

english

File:

PDF, 574 KB

english, 1986

44

Quantitative mRNA analysis of five C-terminal splice variants of the human 5-HT4 receptor in the central nervous system by TaqMan real time RT-PCR

Andrew D. Medhurst, Frank Lezoualc’h, Rodolphe Fischmeister, Derek N. Middlemiss, Gareth J. Sanger,

Journal:

Molecular Brain Research

Year:

2001

Language:

english

File:

PDF, 878 KB

english, 2001

45

The type 2 CCK/gastrin receptor antagonist YF476 acutely prevents NSAID-induced gastric ulceration while increasing iNOS expression

Dominic-Luc Webb, Tobias Rudholm-Feldreich, Linda Gillberg, Md. Abdul Halim, Elvar Theodorsson, Gareth J. Sanger, Colin A. Campbell, Malcolm Boyce, Erik Näslund, Per M. Hellström

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

2013

Language:

english

File:

PDF, 417 KB

english, 2013

46

Potentiation by cholinesterase inhibitors of cholinergic activity in rat isolated stomach and colon

Emma M. Jarvie, Selim Cellek, Gareth J. Sanger

Journal:

Pharmacological Research

Year:

2008

Language:

english

File:

PDF, 573 KB

english, 2008

47

Chronic constipation: improved understanding offers a new therapeutic approach

Sanger, Gareth J.

Journal:

The Journal of Physiology

Year:

2016

Language:

english

File:

PDF, 72 KB

english, 2016

48

Inhibition of Neuromuscular Contractions of Human and Rat Colon by Bergamot Essential Oil and Linalool: Evidence to Support a Therapeutic Action

Straface, Marilisa, Makwana, Raj, Palmer, Alexander, RombolÃ , Laura, Aleong, Joanne Chin, Morrone, Luigi Antonio, Sanger, Gareth J.

Journal:

Year:

2020

File:

PDF, 1.61 MB

2020

49

Gastrointestinal neuropharmacology: identification of therapeutic targets

John B. Furness, Gareth J. Sanger

Journal:

Current Opinion in Pharmacology

Year:

2002

Language:

english

File:

PDF, 36 KB

english, 2002

50

Differential effects of dexamethasone, ondansetron and a tachykinin NK1 receptor antagonist (GR205171) on cisplatin-induced changes in behaviour, food intake, pica and gastric function in rats

Nasser M. Malik, Yong-Ling Liu, Nicholas Cole, Gareth J. Sanger, Paul L.R. Andrews

Journal:

European Journal of Pharmacology

Year:

2007

Language:

english

File:

PDF, 482 KB

english, 2007

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